Odontogenic myxoma of the mandible ramya sree s1, vardendra g kulkarni2, chandrashekhar hr3, shivamurthy kc4 abstract. Odontogenic myxoma om is classified as a locally invasive, nonmetastasizing benign tumor, which presents in 3% to 6% of all odontogenic tumors, of the jaws by world. Odontogenic myxoma om is classified as a locally invasive, nonmetastasizing benign tumor, which presents in 3% to 6% of all odontogenic tumors, of the jaws. The tumor is of mesenchymal origin, and the characteristics of the lesion have been described by various authors in 7l previous reports2. Several tumors exist, which only appear to occur in the jaws. Background odontogenic myxoma om is a benign but locally aggressive and nonmetastasising neoplasm of the jaws. Odontogenic and nonodontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 36% of odontogenic tumors 2. Myxoma as stated is a tumor present near the heart. Cementoma sering ditemukan pd usia myxoma derived from craniofacial bone tissue of facial bones which was previously subdivided into true osteogenic myxoma and odontogenic myxoma. In 1964, marcove et al described the term fibromyxoma. Aggressive tumor, carnoys solution, odontogenic myxoma, odontogenic.
Received 5 july 1983, accepted 4 january 1984 the odontogenic myxoma is a relatively rare benign neoplasm of bone occurring in the jaws. Odontogenic myxoma is a benign, locally aggressive neoplasm of the jaws that was. Odontogenic and nonodontogenic developmental cysts dentigerous cyst odontogenic keratocyst lateral periodontal and botyroid odontogenic cyst gingival cyst glandular odontogenic cyst calcifying odontogenic cyst orthokeratinised odontogenic cyst nasopalatine duct cyst 332 virchows arch 2018 472. Majority of myxomas that occur are present on the left side of the heart. Odontogenic and non odontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. Third most frequent odontogenic tumor after odontoma and ameloblastoma recurrence rate 25% odontogenic myxoma. Earlier in 1947 thoma and goldman first described myxomas of the jaws. Its origin is uncertain but is believed to arise from the mesenchyme of dental papilla 2. Jan 30, 2019 myxoma as stated is a tumor present near the heart. Clinicoradiographic examination of odontogenic myxoma with. Click on the link to view a sample search on this topic. This report describes a case of odontogenic myxoma producing diffusely dispersed calcified products in a pattern. Odontogenic myxomas have a very bland histologic appearance that lacks atypia and may easily lead to misdiagnosis. Pubmed is a searchable database of medical literature and lists journal articles that discuss odontogenic myxoma.
Radiologic and pathologic characteristics of benign and. Although they do not normally contain odontogenic tissue, they are probably odontogenic because of their site of origin. It is nonencapsulated, arises from odontogenic ectomesenchyme, develops solely in the jaws, and represent a small percentage of odontogenic tumor overall. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. This is a case report of odontogenic myxoma in a 32 year old female patient and the treatment rendered to her. Discussion prevalence of odontogenic myxoma accounted to be 0. Clinicoradiographic examination of odontogenic myxoma.
Various authors have suggested en bloc resection due to a concern regarding inadequate clearance while others have suggested more conservative treatment. Odontogenic myxoma of mandible appeared as an ameloblastoma. Myxoma is a tumour that can be found in the heart, skin, subcutaneous cellular tissue and bone. According to the world health organization who, they originate from odontogenic ectomesenchyme, with or without odontogenic epithelium 2 3. Odontogenic and non odontogenic developmental cysts. It presents as a slow growing and locally invasive lesion of the jaw. Odontogenic myxoma is a rare benign but locally aggressive odontogenic tumor. Jaw tumors and cysts symptoms and causes mayo clinic.
At the 1year clinical and radiological follow up there was no sign of recurrence. Background odontogenic myxoma om is a benign but locally aggressive and non metastasising neoplasm of the jaws. May 29, 2014 educational video created by unmc college of dentistry class of 2016 dental students. Dec 09, 2010 odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Epidemiology typically seen in the 2nd to 3rd decades of life slightly earlier than ameloblastomas. Benign odontogenic neoplasm characterized by bland, spindled to stellate cells set in myxoid stroma. A case of a rapidly expanding odontogenic myxoma of the. Odontogenic myxoma of the maxilla a rare case report. New tumour entities in the 4th edition of the world health. Other tumors with myxoid features subtypes include. Odontogenic fibroma dan myxoma terutama terjadi pd umur 2330 tahun merup lesi sentral yg dpt menyebabkan destruksi korteks tulang berhubungan dgn gigi tidak tumbuh atau tidak ada 23. A clinical, radiologic, immunohistochemical, and ultrastructural study.
Based on the clinical, radiographic and histopathological features a final diagnosis of odontogenic myxoma was made. Overall, odontogenic tumors are rare and form only a small proportion of the lesions found in the jaw. Odontogenic myxoma is a rare, benign intraosseous tumor. It is a separate clinical entity11, originating in the mesenchymal, portion of the dental tissues11, and the dental papilla is usually pointed out as its probable. Odontogenic myxoma is a rare tumour of jaw which was first reported by thoma and goldman in 1947. Discussion all the authors claim that odontogenic myxoma is a rare tumor which exclusively affects the maxillofacial region 2,5,10. Treatment, symptoms, causes, complications, diagnosis. Nevertheless, head and neck myxoma is a rare tumor. Odontogenic myxoma is a rare benign tumor unencapsulated aggressive and located character, originating from mesenchymal cells.
Dec 14, 2016 odontogenic fibroma dan myxoma terutama terjadi pd umur 2330 tahun merup lesi sentral yg dpt menyebabkan destruksi korteks tulang berhubungan dgn gigi tidak tumbuh atau tidak ada 23. Focal mucinous degeneration of skin soft tissue may be due to cysts, ganglion, mucinosis, myxedema, nodular fasciitis. Odontogenic myxoma represents an uncommon benign neoplasm comprising of 36% of all odontogenic tumors most commonly arising in the mandible 66. Pdf odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively.
Jaw tumors and cysts, sometimes called odontogenic tumors and cysts, can vary greatly in size and severity. Mesodermal tumors osteoma, gardners syndrome, central hemangioma, av fistula,osteoblastoma, osteoid osteoma. An irregular soft tissue mass lesion is seen arising from right maxillary bone alveolar process, measuring 6 x 4. We present an unusual case of om as a rapidly expanding lesion in the mandible of a 62yearold woman who. No recurrence of tumor has been seen over a period of three years. Odontogenic myxoma genetic and rare diseases information. The majority of the patients with odontogenic myxoma are.
Odontogenic myxoma om is a benign intraosseous tumor, but locally invasive, having a high rate of recurrence. Prevalence rates of odontogenic myxomas ranges between 0. Chapter 21 odontogenic and non odontogenic tumors of the jaws introduction. In one large retrospective study, odontogenic myxoma constituted about 3% of 706 odontogenic tumors regezi, 2002.
Odontogenic myxoma is a rare slow growing, benign, locally aggressive tumor of ectomesenchymal origin with or without odontogenic epithelium, comprising 3%. These growths are usually noncancerous benign, but they can be aggressive and invade the surrounding bone. Odontogenic myxoma international journal of oral health and. Conjunctival myxomas are thought to originate in tenons capsule and can masquerade as conjunctival lymphoma, lymphangioma, ocular surface. Odontogenic myxomas are considered to be a benign odontogenic tumor with locally aggres sive behavior, nonmetastasizing neoplasm of the jaw bones. Odontogenic myxoma segmental mandibulectomy stellate and spindleshaped cells immunohistochemical staining a b s t r a c t odontogenic myxoma om is a rare benign neoplasm with locally aggressive behavior. Pdf odontogenic myxoma om is a locally aggressive, benign, slowgrowing tumor arising from mesenchyme andor odontogenic epithelium. There is no consensus regarding the ideal treatment for odontogenic myxomas, an odontogenic mesenchymal neoplasm.
Dec 11, 2018 jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. Twoyear followup showed no evidence of any recurrence. Cementoma sering ditemukan pd usia odontogenic myxoma is a benign odontogenic tumor with locally aggressive behavior, and is relatively rare in the oral cavity. As a myxoma, this tumor consists mainly of spindle shaped cells and scattered collagen fibers distributed through a loose, mucoid material. The odontogenic myxoma is generally considered to be a rare neoplasm unique to the jaws. These tumors are usually located on the atrial septum. Colman and rinaldo canalis department of oral and maxillofacial surgery and division of otolaryngology, harhorucla medical center, california, usa abstract the odontogenic myxoma is a relatively rare benign tumor occurring in the jaws. It preferably locates in posterior mandibular regions, followed by the incisors, maxillary and. Odontogenic myxoma, odontogenic fibromyxoma, maxilla 1.
In the international histological classification of odontogenic tumors, odontogenic myxoma om is defined as a benign odontogenic tumor of mesenchymal origin that is locally invasive and consists of rounded and angular cells lying in. Mar 19, 2012 the odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. An expanded odontogenic myxoma in maxilla stomatologija. Pdf odontogenic myxoma of the mandible researchgate. Maiuri f, corriero g, galicchio b, angrisani p, bonavolonta g.
Recontruction surgery of the mandible was also done. Odontogenic myxoma om of the jaw is the fourth most common odontogenic tumour and represents 36% of all odontogenic tumours. Odontogenic fibromyxoma is slow growing, non encapsulated, benign lesion of jaw with rare occurrence. Odontogenic myxoma can be found most often in young adults aged 2535 years although lesions may occur over a lifetime, reporting the lowest. Odontogenic myxoma is an uncommon benign mesenchymal odontogenic tumor arising from the dental papilla, follicle, or the periodontal ligament.
This study evaluated the literature concerning the surgical management of odontogenic myxoma, and reports the longterm outcome of a case managed. Who histological classification of odontogenic and. Educational video created by unmc college of dentistry class of 2016 dental students. Odontogenic myxoma represents an uncommon benign neoplasm comprising of 36% of all odontogenic tumors most commonly arising in. Odontogenic myxoma is a rare tumour of the jaw, making both its diagnosis and management challenging. This wide variation in incidence may be attributed to the rarity of the lesion. We present a case managed by buccal cortical resection and an iliac crest bone graft. Reported incidence rates of odontogenic myxoma range from 0. Odontogenic myxomas are benign but locally aggressive neoplasms found almost exclusively in the jaws and arise only occasionally in other bones. The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue associated with tooth formation. The occurrence of om in children is uncommon and rarely involves the orbit. Presentasi kista odontogenik dan tumor odontogenik willi.
This paper reports a 6year followup case of an odontogenic myxoma treated with wide resection and mandibular bone reconstruction for posterior rehabilitation with dental implants. Odontogenic myxoma of the maxilla a rare case report ramkumar subramaiam, 1 sangeetha narashiman, 2 malathi narasimhan, 3 veda giri, 4 and santhosh kumar 5 1 professor, department of oral and maxillofacial surgery, faculty of dental sciences, sri ramachandra university, ramachandra nagar, porur chennai, tamilnadu, india. Odontogenic myxoma is a rare, benign, locally aggressive and non metastasizing neoplasm which is believed to arise from the odontogenic ectomesenchyme and bears a close microscopic resemblance to mesenchymal portion of a tooth germ. Benign odontogenic myxoid lesion composed of spindled to stellate cells. Lo muzio l, nocini p, favia g, procaccini m, mignogna md. There are currently no clear surgical management guidelines for odontogenic myxoma, and a variety of approaches may be used. Chapter 21 odontogenic and nonodontogenic tumors of the jaws introduction. In the majority of cases, diagnosis is largely dependent on the histopathological findings. Odontogenic myxoma om is classified as a locally invasive, non metastasizing benign tumor, which presents in 3% to 6% of all odontogenic tumors, of the jaws by world. Myxoma is a rare, benign stromal tumor of mesenchymal origin often confused with other conjunctival stromal tumors. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Odontogenic ectomesenchyme with or without included odontogenic epithelium odontogenic.
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